Autor:	J, Beastall, R H, Guy, J, Hadgraft, I, Wilding
Rok vydání:	2013
Zdroj:	Pharmaceutical research. 3(5)
ISSN:	0724-8741
Popis:	The release characteristics of aqueous and oily creams (BP) containing urea up to concentrations of 10% have been studied. The results show that the urea has little influence on the ability of the formulation to release its active ingredient, in this case, hexyl nicotinate. The preparations were then assessed in an in vivo experiment by measuring the time of onset of erythema induced by the hexyl nicotinate. The urea influenced the time of onset of erythema, and a mechanism for its action is proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3fb3562923bbadbdef9ef957b53d7124 https://pubmed.ncbi.nlm.nih.gov/24271713 Zobrazit plný text záznamu Full text from SpringerLink