Haemoglobin concentrations and infection by Giardia intestinalis in children: effect of treatment with secnidazole

Autor: J C, Jiménez, N, Rodríguez, M C, Di Prisco, N R, Lynch, V, Costa
Rok vydání: 2000
Předmět:
Zdroj: Annals of tropical medicine and parasitology. 93(8)
ISSN: 0003-4983
Popis: The blood concentrations of haemoglobin were investigated in 82 children aged 2-9 years. Fifty-seven (31 boys and 26 girls) were stool-positive for Giardia intestinalis but the other 25, used as controls, were negative. The mean (S.D.) haemoglobin concentration among the infected children was significantly lower pre-treatment than that for the control group [11.6 (1.2) v. 12.6 (1.5) g/dl; P0.05]. Treatment of the infected children with a single oral dose of secnidazole (30 mg/kg) led to a significant increase in their mean haemoglobin level 15 days later, from 11.6 (1.2) g/dl pre-treatment to 12.4 (1.2) g/dl post-treatment (P0.05). The results indicate that the therapeutic control of giardiasis could be important in programmes to combat anaemia in children living in endemic areas.
Databáze: OpenAIRE