| Autor: |
A, Anesi, D, Franciotta, E, Di Paolo, E, Zardini, G V, Melzi d'Eril, F, Zerbi |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Functional neurology. 9(1) |
| ISSN: |
0393-5264 |
| Popis: |
We measured some immunological parameters in 20 hospitalized patients with major depression and 20 age- and sex-matched healthy controls. Both enumeration of immune cells, including T-lymphocyte subpopulations, and assay of T-cell function were studied. White blood cells were evaluated with an automated cell counter, T-cell subsets with an immunobead technique, and T-cell function with a phytohemagglutinin-induced proliferation in vitro assay. We found that T-lymphocyte responses to the mitogen were significantly lower in depressed patients than in controls. All the other parameters were normal. These findings suggest that functional but not numerical changes in T-lymphocytes characterize major depressive disorders. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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