[Mechanisms of the antiaggregation activity of 1,4-naphthoquinone derivatives]

Autor:	G S, Levin, I B, Kalmykova, V B, Shneĭvaĭs, Ts L, Kamenetskaia, Ia Ia, Dregeris
Rok vydání:	1989
Předmět:	Plasma Vitamin K Dose-Response Relationship Drug Platelet Aggregation Luminescent Measurements Humans Vitamin K 3 Butylated Hydroxytoluene In Vitro Techniques Antioxidants Platelet Aggregation Inhibitors Naphthoquinones
Zdroj:	Farmakologiia i toksikologiia. 52(5)
ISSN:	0014-8318
Popis:	The antiaggregation effects of synthetic derivatives of 1,4-naphtoquinone and ionol were studied as compared with the antioxidant properties of the agents. The proportional relationship was shown to exist between the antiaggregation properties of the compounds and their antiradical activity under conditions of the interaction with biosubstrates. The data obtained suggest that the derivatives of 1,4-naphtoquinone with the intramolecular transfer of the charge are promising antiaggregation agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3e9633e69f728828a3ac9853e53c06f6 https://pubmed.ncbi.nlm.nih.gov/2599075 Zobrazit plný text záznamu