| Autor: |
Bei, Jia, Chenchen, Zhao, Kevin L, Rakszawski, David F, Claxton, W Christopher, Ehmann, Witold B, Rybka, Shin, Mineishi, Ming, Wang, Hiroko, Shike, Michael G, Bayerl, Jeffrey M, Sivik, Todd D, Schell, Joseph J, Drabick, Raymond J, Hohl, Hong, Zheng |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Cancer research. 79(7) |
| ISSN: |
1538-7445 |
| Popis: |
Acute myeloid leukemia (AML) is a devastating blood cancer with poor prognosis. Immunotherapy targeting inhibitory pathways to unleash the antileukemia T-cell response is a promising strategy for the treatment of leukemia, but we must first understand the underlying molecular mechanisms. Eomesodermin (Eomes) and T-bet are both T-box transcription factors that regulate CD8 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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