| Autor: |
S, Arimori, K, Koriyama, K, Hiramatsu, Y, Shimizu, Y, Matsumura |
| Rok vydání: |
1980 |
| Předmět: |
|
| Zdroj: |
The Tokai journal of experimental and clinical medicine. 5(4) |
| ISSN: |
0385-0005 |
| Popis: |
Decreases in numbers and functions of SLE T lymphocytes as a form of lymphoreceptopathy were investigated using T lymphocytes and sera obtained from both SLE patients and healthy subjects with respect to the effects of suppressor T cells and Con A induced suppressor factor against antibody formation, changes in the membrane microviscosity and the ultrastructure of membrane associated particles (MAPs) of T lymphocytes. The lymphoreceptopathy of SLE T lymphocytes was induced by decreased microviscosity and abnormalities of distribution, size and density of MAPs on the T lymphocyte membrane which can be modulated by serum factors consisting mainly of IgG as T cell membrane binding antibody and partially of IgM as cytotoxic antibody. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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