| Autor: |
Seiji, Tokumitsu, Hiroaki, Oka, Akira, Nozaki, Takeo, Kanazawa, Yasuko, Mukohara, Masahide, Matsubara, Kenji, Matsushita, Takehiko, Tsunashima |
| Rok vydání: |
2008 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 35(12) |
| ISSN: |
0385-0684 |
| Popis: |
A-58-year-old female admitted to our hospital for abdominal fullness and dyspnea was diagnosed with malignant pleuro-peritonitis of advanced ovarian cancer. CT showed a massive right-sided pleural effusion, massive ascites, and large ovarian tumor (about 10 x 15 cm). The patient was treated with intrathoracic administration of CDDP and CPT-11. Combination chemotherapy of CDDP (10 mg/week) and CPT-11 (10 mg/week) was administered by intrapleural injection every other week. As a result (total amount; CDDP 310 mg, CPT-11 250 mg, in 9 months), pleural effusion and ascites disappeared. Moreover, marked shrinkage (about 3 x 4 cm) of the tumor was confirmed. This intrathoracic administration of CDDP and CPT-11 may be an effective loco-regional therapy for advanced ovarian cancer with malignant pleuro-peritonitis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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