Heart failure: clinical problem and management issues

Autor: John M, Nicklas, Barry E, Bleske, Richard, Van Harrison, Robert V, Hogikyan, Yeong, Kwok, William E, Chavey
Rok vydání: 2013
Předmět:
Zdroj: Primary care. 40(1)
ISSN: 1558-299X
Popis: Heart failure (HF) often presents as dyspnea either with exertion and/or recumbency. Patients also experience dependent swelling and fatigue. Measurement of the left ventricular ejection fraction (LVEF) identifies HF patients who may respond to pharmacologic therapy and/or electrophysiologic device implantation. Angiotension converting enzyme inhibitors, beta blockers, and aldosterone inhibitors can significantly lower the mortality and morbidity of HF in patients with an LVEF less than 35%. Cardiac defibrillators and biventricular pacemakers can also improve outcomes in selected patients with a decreased LVEF. The authors provide a guide for therapeutic decisions based on the inclusion criteria of the major clinical trials.
Databáze: OpenAIRE