A Retrospective Review of Tofacitinib in the Treatment of Refractory Dermatomyositis

Autor: John, Plante, Chelsea, Eason, Gabriella, Santa Lucia, India, Robinson, Dirk, Elston
Rok vydání: 2022
Předmět:
Zdroj: Journal of drugs in dermatology : JDD. 21(10)
ISSN: 1545-9616
Popis: Dermatomyositis (DM) is an autoimmune myopathy with characteristic dermatologic features.1 Tofacitinib is an immunomodulator with proven efficacy against numerous immune-mediated disorders, including rheumatoid arthritis (RA) and psoriasis.2 Several reports have demonstrated oral tofacitinibrsquo;s ability to treat the cutaneous and extracutaneous manifestations of refractory dermatomyositis (DM).1,4,5 However, evidence for sustained improvement remains limited.2,3 The goal of this study is to investigate the long-term response of recalcitrant DM to oral and topical tofacitinib at varied dosing regimens.
Databáze: OpenAIRE