Autor: |
John, Plante, Chelsea, Eason, Gabriella, Santa Lucia, India, Robinson, Dirk, Elston |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Journal of drugs in dermatology : JDD. 21(10) |
ISSN: |
1545-9616 |
Popis: |
Dermatomyositis (DM) is an autoimmune myopathy with characteristic dermatologic features.1 Tofacitinib is an immunomodulator with proven efficacy against numerous immune-mediated disorders, including rheumatoid arthritis (RA) and psoriasis.2 Several reports have demonstrated oral tofacitinibrsquo;s ability to treat the cutaneous and extracutaneous manifestations of refractory dermatomyositis (DM).1,4,5 However, evidence for sustained improvement remains limited.2,3 The goal of this study is to investigate the long-term response of recalcitrant DM to oral and topical tofacitinib at varied dosing regimens. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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