RNA Chemical Proteomics Reveals the N
| Autor: | A Emilia, Arguello, Amanda N, DeLiberto, Ralph E, Kleiner |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Proteomics
Adenosine DNA Helicases AlkB Homolog 5 RNA Demethylase RNA-Binding Proteins Cell Cycle Proteins Neoplasm Proteins Fragile X Mental Retardation Protein RNA Recognition Motif Proteins Humans RNA Carrier Proteins Poly-ADP-Ribose Binding Proteins Ubiquitin Thiolesterase RNA Helicases Adaptor Proteins Signal Transducing |
| Zdroj: | Journal of the American Chemical Society. 139(48) |
| ISSN: | 1520-5126 |
| Popis: | Epitranscriptomic RNA modifications can regulate mRNA function; however, there is a major gap in our understanding of the biochemical mechanisms mediating their effects. Here, we develop a chemical proteomics approach relying upon photo-cross-linking with synthetic diazirine-containing RNA probes and quantitative proteomics to profile RNA-protein interactions regulated by N |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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