Systemic medication and the inflammatory cascade

Autor:	Aws, Alani, Robin, Seymour
Rok vydání:	2013
Předmět:	Periodontium Adrenal Cortex Hormones Anti-Inflammatory Agents Humans Cyclooxygenase Inhibitors Hydroxymethylglutaryl-CoA Reductase Inhibitors Inflammation Mediators Periodontitis Immunosuppressive Agents
Zdroj:	Periodontology 2000. 64(1)
ISSN:	1600-0757
Popis:	Periodontal disease is caused by inflammatory processes initiated by the presence of a biofilm. The management of this disease process is largely achieved by disrupting the biofilm to allow regression of inflammation and healing. As our patients are living for longer they are likely to have been exposed to systemic medications that aim to reduce inflammation. These drugs have been shown to decrease inflammation within the periodontal tissues despite not being a primary function of their use. This paper aims to review the relative effects of common systemic medications on the periodontal tissues by analyzing their modes of action and discussing current research and the implications for periodontal treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3d4dcb78a27fe080bd839e3882c7fa7d https://pubmed.ncbi.nlm.nih.gov/24320964 Zobrazit plný text záznamu Plný text