[The effect of sympathetic denervation on the structure, contractility and electrical activity of the smooth-muscle cells in the cat nictitating membrane]

Autor:	R Kh, Akhmedzianov, Iu A, Chelyshev, R S, Nizamov
Rok vydání:	1991
Předmět:	Microscopy Electron Norepinephrine Sympathetic Nervous System Cats Action Potentials Animals Muscle Smooth Nictitating Membrane Ganglionectomy Muscle Contraction Potassium Chloride
Zdroj:	Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 77(11)
ISSN:	0015-329X
Popis:	The nucleus and soma of sympathetically denervated smooth muscle cells (SMCs) of the cat nictitating membrane were found to be enlarged. The number of free ribosomes was dramatically increased and a disintegration of microfilaments was found. The functional changes involved spontaneous or agonist-induced generation of APs. These findings suggest that the denervation destructed the adrenoreceptor control mechanisms of the excitable membrane's potential. The possibility of emergence of new Ca2+ channels in the denervated SMCs is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3d4d0cd470bc9bda307f930b76d557f6 https://pubmed.ncbi.nlm.nih.gov/1668666 Zobrazit plný text záznamu