Acute respiratory infections due to enterovirus 68 in Yamagata, Japan between 2005 and 2010

Autor:	Tatsuya, Ikeda, Katsumi, Mizuta, Chieko, Abiko, Yoko, Aoki, Tsutomu, Itagaki, Fumio, Katsushima, Yuriko, Katsushima, Yoko, Matsuzaki, Naoko, Fuji, Tadatsugu, Imamura, Hitoshi, Oshitani, Masahiro, Noda, Hirokazu, Kimura, Tadayuki, Ahiko
Rok vydání:	2012
Předmět:	Enterovirus D Human Male Adolescent Japan Child Preschool Molecular Sequence Data Enterovirus Infections Humans Infant Female Child Respiratory Tract Infections Phylogeny
Zdroj:	Microbiology and immunology. 56(2)
ISSN:	1348-0421
Popis:	To clarify the epidemiology of enterovirus 68 (EV68), which is one of the most rarely identified enteroviruses, virus isolation and molecular screening using RT-PCR was performed on 6307 respiratory specimens collected at pediatric clinics in Yamagata, Japan between 2005 and 2010. In the years 2005-2009, 10, 1, 2, 0, and 2 (40) EV68-positive cases, respectively, were identified by RT-PCR. In 2010, 40 cases were identified altogether: 2 by isolation only, 26 by RT-PCR only, and 12 by both isolation and RT-PCR. Phylogenetic analysis indicated that plural genetically distinct clusters co-circulated. These results suggest that that difficulty in EV68 isolation leads to an underestimation of the prevalence of EV68 infections.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3d2da3eba5fe4fb31ec9d622b550d830 https://pubmed.ncbi.nlm.nih.gov/22309616 Zobrazit plný text záznamu Plný text