Autor: |
T, Suzuki, Y, Shiozaki, Y, Masukawa, M, Misawa |
Rok vydání: |
1992 |
Předmět: |
|
Zdroj: |
Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studiesdrug dependence. 27(1) |
ISSN: |
0389-4118 |
Popis: |
The effects of calcium antagonists (nifedipine, flunaridine and diltiazem) on the cocaine- and methamphetamine-induced place preference were examined. Calcium antagonists alone induced neither place preference nor place aversion. Nifedipine markedly antagonized and flunarizine and diltiazem reduced the cocaine-induced place preference. The methamphetamine-induced place preference was reduced by nifedipine and diltiazem, but not by flunarizine. These results suggest the possibility that the cocaine-induced place preference is strongly influenced by dihydropyridine sensitive calcium channels, whereas the methamphetamine-induced place preference is not. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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