'A comparison of the effectiveness of two hypnotic agents for the treatment of insomnia'
Autor: | Thomas, Schwartz, Nikhil, Nihalani, Subhdeep, Virk, Shefali, Jindal, Anne, Costello, Ray, Muldoon, Nouman, Azhar, Juhi, Hussein, Syed, Tirmazi |
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Rok vydání: | 2004 |
Předmět: |
Adult
Male Inpatients Time Factors Adolescent Mental Disorders Administration Oral Pilot Projects Middle Aged Pyrimidines Treatment Outcome Sleep Initiation and Maintenance Disorders Trazodone Acetamides Humans Hypnotics and Sedatives Female Prospective Studies Drug Monitoring Selective Serotonin Reuptake Inhibitors Aged |
Zdroj: | The international journal of psychiatric nursing research. 10(1) |
ISSN: | 0968-0624 |
Popis: | To compare the effectiveness and tolerability of two hypnotic agents, trazadone (Desyrel) and zaleplon (Sonata) on psychiatric inpatients with insomnia.Fifteen patients who were psychiatric inpatients were assigned openly and randomly to receive either trazodone (50-100 mg) or zaleplon (10-20 mg) doses on an "as-needed basis" and followed throughout their hospital stay. Efficacy and side effect profile were subsequently assessed.This pilot study suggests that trazodone may be a better agent to promote longer, deeper subjective quality sleep for psychiatric inpatients with insomnia in terms of effectiveness. However, tolerability was much better with zaleplon as daytime residual side effects were less. |
Databáze: | OpenAIRE |
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