Metabolic Screening in Children with Neurodevelopmental Delay, Seizure and/or Regression
| Autor: | KARIMZADEH, Parvaneh, TAGHDIRI, Mohammad Mahdi, ABASI, Ezatollah, HASSANVAND AMOUZADEH, Masoud, NAGHAVI, Zhila, GHAZAVI, Ahad, NASEHI, Mohammad Mahdi, ALIPOUR, Abbas |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Iranian Journal of Child Neurology |
| ISSN: | 2008-0700 1735-4668 |
| Popis: | Objective Neurometabolic disorder is one of the important groups of diseases that prominently has presentation early infantile period. In this study, we evaluated the result of metabolic screening of the patient with seizure, developmental delay and/or regression in development, demographic disease clinical and radiological findings on admitted and outpatient visited children. Materials & Methods Two-year retrospective review of 187 children with seizure, developmental delay and/or regression in the Mofid Children Hospital, Tehran, Iran was performed. The diagnosis was based on observation, findings of EEG and history of the patient, besides evaluation of patient milestones. The result of metabolic screening with Tandem mass spectrometry was evaluated using SPSS (ver.18.0) Statistical software. Results Totally, 187 children with seizure, regression and/or developmental delay were evaluated by metabolic screening with tandem mass spectrometry method. The results of laboratory examination had no relationship between positive results of metabolic screening and the mentioned disease. The relations between positive results of metabolic screening and seizure, regression and/or developmental delay were not statistically meaningful. Conclusion Positive results of metabolic screening and seizure, regression and/or developmental delay were not statistically meaningful. |
| Databáze: | OpenAIRE |
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