The impact of the COVID-19 pandemic on the delivery of primary percutaneous coronary intervention in STEMI

Autor: Kristina, Frain, Krishnaraj S, Rathod, Ebrahiem, Tumi, Yang, Chen, Stephen, Hamshere, Fizzah, Choudry, Mohammed M, Akhtar, Miles, Curtis, Rajiv, Amersey, Oliver, Guttmann, Constantinos, O'Mahony, Ajay, Jain, Andrew, Wragg, Andreas, Baumbach, Anthony, Mathur, Daniel A, Jones, Paul, Rees
Rok vydání: 2021
Předmět:
Zdroj: Am J Cardiovasc Dis
ISSN: 2160-200X
Popis: Objectives: The clinical environment has been forced to adapt to meet the unprecedented challenges posed by the COVID-19 pandemic. Intensive care facilities were expanded in anticipation of the pandemic where the consequences include severe delays in elective procedures. Emergent procedures such as Percutaneous Coronary Intervention (PCI) in acute myocardial infarction (AMI) in which delays in timely delivery have well established adverse prognostic effects must also be explored in the context of changes in procedure and public behaviour associated with the COVID-19 pandemic. The aim for this single centre retrospective cohort study is to determine if door-to-balloon (D2B) times in PCI for ST Elevation Myocardial Infarction (STEMI) during the United Kingdom’s first wave of the COVID-19 pandemic differed from pre-COVID-19 populations. Methods: Data was extracted from our single centre PCI database for all patients that underwent pPCI for STEMI. The reference (Pre-COVID-19) cohort was collected over the period 01-03-2019 to 31-05-2019 and the exposure group (COVID-19) over the period 01-03-2020 to 31-05-2020. Baseline patient characteristics for both populations were extracted. The primary outcome measurement was D2B times. Secondary outcome measurements included: time of symptom onset to call for help, transfer time to first hospital, transfer time from non-PCI to PCI centre, time from call-to-help to PCI centre, time to table and onset of symptoms to balloon time. Categorical and continuous variables were assessed with Chi squared and Mann-Whitney U analysis respectively. Procedural times were calculated and compared in the context of heterogeneity findings. Results: 4 baseline patient characteristics were unbalanced between populations with statistical significance (P
Databáze: OpenAIRE