[Rechallenge of everolimus for metastatic renal cell carcinoma after recovery from grade 3 interstitial lung disease: a case report]

Autor: Noriaki, Utsunomiya, Yuka, Kono, Keiyu, Matsumoto, Takeshi, Matsumoto, Atsushi, Nakagawa, Hiroyuki, Tsunemori, Takuya, Okada, Koei, Muguruma, Mutsushi, Kawakita
Rok vydání: 2014
Předmět:
Zdroj: Hinyokika kiyo. Acta urologica Japonica. 60(1)
ISSN: 0018-1994
Popis: We report a case of the rechallenge of everolimus for metastatic renal cell carcinoma (RCC) after successful recovery from grade 3 interstitial lung disease (ILD). A 76-year-old man with metastatic RCC developed grade 3 ILD one month after the initiation of everolimus therapy (10 mg/day). ILD subsided in 4 months after the withdrawal of everolimus and treatment with corticosteroids. Half dose (5 mg/day) of everolimus was rechallenged for 9 months until another grade 3 ILD developed. Everolimus kept the disease under control for 13 months including the discontinuation period.
Databáze: OpenAIRE