[Effects of lidocaine on intramural circulation in isolated rabbit heart ventricle preparations]

Autor:	V G, Fast, A M, Pertsov, T B, Efimova
Rok vydání:	1990
Předmět:	Heart Conduction System Heart Ventricles Animals Lidocaine Ventricular Function Arrhythmias Cardiac Rabbits In Vitro Techniques
Zdroj:	Kardiologiia. 30(10)
ISSN:	0022-9040
Popis:	Mapping was used on isolated rabbit ventricular specimens to study effects of lidocaine, 2-8 mg/l, on persistent intramural reentry involving the areas of slow transmural conduction. The agent was shown to produce antiarrhythmic and arrhythmogenic effects at the same time. Lidocaine reduced the duration of an arrhythmia, but provoked its initiation. Both these effects of lidocaine were attributable to its action on the refractory period of a slow transmural conduction area.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3c6f6677168c5a3304c18e1697e31c6b https://pubmed.ncbi.nlm.nih.gov/2290284 Zobrazit plný text záznamu