| Autor: |
N R, Mirzoian, V P, Akopian, A Zh, Kocharian, V A, Knarian, L N, Arakelian, G A, Gevorkian |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia. 61(5) |
| ISSN: |
0869-2092 |
| Popis: |
Studies showed that 15-day restriction of motor activity inhibits the reuptake of GABA by sections of the rat brain cortex and hypothalamus. In prolonged intraperitoneal injection of 10 mg/kg cinnarizine in hyperkinesia, further inhibition of this process in hypothalamic sections is encountered on the 15th days. Flunarizin (1 mg/kg) administered in a like manner has no significant effect on GABA reuptake. A course of GABA injections in a dose of 5 mg/kg improves in rats with restricted motor activity the local blood flow in the frontal lobe of the brain. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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