Hepatitis C virus-associated pericardial effusion and tamponade in a liver transplant recipient

Autor: Lazaros A, Nikolaidis, Maher, Azzouz, Lois, Friedlander, David H, Van Thiel, Alan H, Gradman
Rok vydání: 2004
Předmět:
Zdroj: The Canadian journal of cardiology. 20(7)
ISSN: 0828-282X
Popis: A liver transplant recipient with hepatitis C presented with unexplained dyspnea, fatigue and edema. Diagnostic evaluation revealed a pericardial effusion with echocardiographic features of tamponade. The patient underwent therapeutic pericardial drainage, resulting in symptomatic relief. The pericardial fluid tested positive for hepatitis C virus (viral quantitation of 200,000 copies/mL, genotype 1b) and negative for other plausible etiologies. Pericardial biopsy revealed normal tissue. This is the fifth case of hepatitis C virus-associated pericardial disease worldwide and the first case in North America. It is the first in a liver transplant recipient. In contrast to previous reports, this patient demonstrated tamponade in the absence of cryoglobulinemia or systemic extrahepatic manifestations of hepatitis C.
Databáze: OpenAIRE