[Hepatoprotective effects of amino acids with branched hydrocarbon chains and taurine in experimental subchronic alcohol intoxication and ethanol withdrawal]

Autor: Iu E, Razvodovskiĭ, E M, Doroshenko, N I, Prokopchik, V Iu, Smirnov, S Iu, Ostrovskiĭ
Rok vydání: 2004
Předmět:
Zdroj: Biomeditsinskaia khimiia. 50(1)
ISSN: 2310-6972
Popis: Forced alcoholization of rats according to Majchrowicz led to the development of fatty liver. The subsequent ethanol withdrawal was accompanied by amino acid imbalance in the pool of free sulfur-containing and glycogenic amino acids in liver and blood plasma. Similar changes were observed after prolonged alcohol intoxication. Intragastric administration of the amino acid composition containing branched-chain amino acids and taurine corrected the amino acid imbalance and reduced the development of the steatosis of the liver.
Databáze: OpenAIRE