'Visualization' of pain using cerebral

Autor: Christian Christensen, Støttrup, Caius Holst, Mortensen, Reza, Piri, Mohsen, Khosravi, Andrew, Newberg, Mikkel Østerheden, Andersen, Abass, Alavi, Peter, Grupe, Poul Flemming, Høilund-Carlsen
Rok vydání: 2022
Zdroj: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society.
ISSN: 1432-0932
Popis: We hypothesized that unilateral leg pain following surgical treatment of lumbar disc herniation (LDH) is associated with an increase in the glucose metabolism of the contralateral thalamus.Patients scheduled for surgery due to LDH underwentTwenty-six patients (ten females) aged 49.7 ± 7.4 (mean ± SD) years were included. There was a significant correlation between painful body side and increased contralateral thalamic uptake of FDG, with regard to cSUVmean values. Correlation analyses including clinical parameters and cSUVmean indicated some association with 1-year change in EQ-5D.These preliminary data sustain the hypothesis that unilateral pain in patients with LDH is associated with increased glucose metabolism in the contralateral thalamus, suggesting a central role of thalamus in chronic pain perception.
Databáze: OpenAIRE