| Autor: |
YAMAGUCHI, Junya, MOTOMURA, Kazuya, OHKA, Fumiharu, AOKI, Kosuke, TANAHASHI, Kuniaki, HIRANO, Masaki, CHALISE, Lushun, NISHIKAWA, Tomohide, SHIMIZU, Hiroyuki, NATSUME, Atsushi, WAKABAYASHI, Toshihiko, SAITO, Ryuta |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
NMC Case Report Journal |
| ISSN: |
2188-4226 |
| Popis: |
Glioblastoma multiforme (GBM) is an aggressive cancer type, with fewer than 3–5% of patients surviving for more than 3 years. We describe a 48-year-old right-handed man who presented with generalized seizure attacks. Magnetic resonance imaging (MRI) revealed a heterogeneous gadolinium-enhancing lesion in the left inferior parietal lobule. The patient underwent awake surgery, and tumor resection included abnormalities on T2-weighted MRI, with subcortical mapping used to identify the deep functional boundaries. After supratotal resection, the tumor was diagnosed as GBM without isocitrate dehydrogenase (IDH) 1 and 2 mutations. At a follow-up evaluation, 9 years and 2 months after the surgery, the patient appeared healthy, and no relapse or recurrence was observed. We present the case of a long-term survivor of IDH-wildtype GBM. This case suggests that supratotal resection with intraoperative awake brain mapping can improve survival without impairing the patient’s neurological functions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
