| Autor: |
Olfat G, Shaker, Omayma O, Abdelaleem, Nermeen A, Fouad, Amani M El Amin, Ali, Tarek I, Ahmed, Enas G, Ibrahem, Noha K, Abdelghaffar |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 39(7) |
| ISSN: |
1557-7465 |
| Popis: |
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease. We aimed to measure the level of miR-155 and its genetic variant rs767649 in patients with RA and to evaluate their relationship with ischemia-modified albumin (IMA). The study was performed on 79 patients with RA (group I) and 78 healthy control participants (group II). Quantitative real-time polymerase chain reaction was used to assess the expression of serum miR-155 in addition to its functional variant rs767649. IMA levels were measured by enzyme-linked immunosorbent assay. Significant overexpression of miR-155 and higher levels of IMA were detected in patients with RA compared with those in controls ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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