| Autor: |
W Randal, Kilgore, Michael S, Spensley, Fangshi, Sun, Robert G, Nutsch, Kathleen A, Rooney, Terry L, Skogerboe |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Veterinary therapeutics : research in applied veterinary medicine. 6(2) |
| ISSN: |
1528-3593 |
| Popis: |
Efficacy and field safety of tulathromycin administered as a single-dose treatment to crossbreed beef calves with undifferentiated bovine respiratory disease (BRD) were evaluated in a multicenter field study conducted at four US feedlots. Two hundred castrated male calves were enrolled at each study site. The treatment groups were physiologic saline (n = 160) given SC at 0.02 ml/kg, tulathromycin (n = 320) given SC at 2.5 mg/kg, and tilmicosin (n = 320) given SC at 10 mg/kg. Nasopharyngeal swabs for bacterial culture were obtained before treatment. The cure rate for calves treated with tulathromycin (78%) and tilmicosin (65%) was significantly (Por = .0001) higher than that of calves treated with saline (23.8%). The cure rate of calves treated with tulathromycin (78.4%) was significantly (P = .0007) higher than that of calves treated with tilmicosin (64.9%). No adverse events related to tulathromycin were reported. Under the conditions of this study, tulathromycin administered as a single-dose treatment was efficacious in the treatment of undifferentiated BRD. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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