| Autor: |
O N, Savchenko, N A, Arutiunian, N I, Beskrovnaia, R G, Levchenko, G F, Khrustaleva |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Problemy endokrinologii. 36(1) |
| ISSN: |
0375-9660 |
| Popis: |
A study of the level of the sex steroid receptors in the endometrium of women with the syndrome of insufficiency of the luteal phase of the cycle (ILP-syndrome) has shown that disorders of receptor processes affect, first of all, progesterone receptors. An increase in a degree of a delay of endometrial development was accompanied by a rise of the level of progesterone in the endometrium which depended on the estradiol-progesterone ratio in the circulation, detectable on the 20th day of the menstrual cycle. The ILP-syndrome is characterized by the sufficient induction of progesterone receptors at the end of the proliferative--the beginning of the luteal phase of the cycle and by their insufficient inhibition with a low level of progesterone in the middle of the luteal phase. Insufficient synthesis of receptors as a result of sharp hypoestrogenemia is less frequent. The primary affection of the receptor apparatus as a cause of the ILP-syndrome against a normal hormonal background in the examinees was undetectable. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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