Argonaute 2 modulates EGFR-RAS signaling to promote mutant

Autor: Ronald F, Siebenaler, Seema, Chugh, Jessica J, Waninger, Vijaya L, Dommeti, Carson, Kenum, Malay, Mody, Anudeeta, Gautam, Nidhi, Patel, Alec, Chu, Pushpinder, Bawa, Jennifer, Hon, Richard D, Smith, Heather, Carlson, Xuhong, Cao, John J G, Tesmer, Sunita, Shankar, Arul M, Chinnaiyan
Rok vydání: 2022
Zdroj: PNAS nexus. 1(3)
ISSN: 2752-6542
Popis: Activating mutations in RAS GTPases drive nearly 30% of all human cancers. Our prior work described an essential role for Argonaute 2 (AGO2), of the RNA-induced silencing complex, in mutant
Databáze: OpenAIRE