[Suppression of translation in vitro of the mRNA of the M1 protein of influenza virus using antisense oligonucleotides]

Autor:	V V, Vlasov, V V, Gorn, N Iu, Nomokonova, T N, Fokina, L V, Iurchenko
Rok vydání:	1991
Předmět:	Viral Matrix Proteins Base Sequence Influenza A virus Protein Biosynthesis Molecular Sequence Data Animals Autoradiography RNA Viral Electrophoresis Polyacrylamide Gel RNA Messenger Rabbits Oligonucleotides Antisense
Zdroj:	Molekuliarnaia biologiia. 25(5)
ISSN:	0026-8984
Popis:	Effect of antisense oligonucleotides on the in vitro translation of the influenza virus M1 protein mRNA was investigated. The most efficient arrest of mRNA translation was achieved by simultaneous action of two or three oligonucleotides (14-16-mers) complementary to the juxtaposed sequences in the 5'-terminus of the molecule around and upstream of the initiation codon.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3a0bdef4cc8d6029f01422fa44293b72 https://pubmed.ncbi.nlm.nih.gov/1753959 Zobrazit plný text záznamu