HIV type 1 subtypes in Malaysia include B, C, and E

Autor: T M, Brown, K E, Robbins, M, Sinniah, T S, Saraswathy, V, Lee, L S, Hooi, B, Vijayamalar, C C, Luo, C Y, Ou, J, Rapier, G, Schochetman, M L, Kalish
Rok vydání: 1996
Předmět:
Zdroj: AIDS research and human retroviruses. 12(17)
ISSN: 0889-2229
Popis: Peripheral blood mononuclear cell specimens were collected from 13 HIV-1-infected IV drug users in Kuala Lumpur, Malaysia, as well as one HIV-infected baby, between 1992 and 1993. DNA was then amplified by nested polymerase chain reaction and a 345-bp fragment of the C2V3 region of the env gene was sequenced. 11 of the 14 Malaysian sequences clustered with the B' subtype, one different from the typical subtype B US strains HIVMN and HIVSF2. Two sequences grouped in the C subtype and had sister taxa closer to the Indian C subtype sequences than those from Zambia. The sequence from the infant was identified as a subtype E virus, grouped more closely with subtype E strains from Thailand than subtype E viruses from the Central African Republic.
Databáze: OpenAIRE