Synthesis of 5a,5a'-dicarba-d-glucobioses from conformationally restricted carbaglucosyl triflates using S

Autor:	Naoya, Tateda, Katsumi, Ajisaka, Masaji, Ishiguro, Tatsuo, Miyazaki
Rok vydání:	2018
Předmět:	Mesylates Molecular Conformation Cyclohexanols Disaccharides
Zdroj:	Bioorganicmedicinal chemistry. 27(12)
ISSN:	1464-3391
Popis:	Novel carbohydrate mimics were designed which contain two 5a-carba-d-glucose residues, one each at reducing and nonreducing end, and thus these mimics are 5a,5a'-dicarba-d-glucobioses. Dicarbadisaccharides have attractive features such as stability against endogenous degradative enzymes and being resistant to glycation reactions such as the Maillard reaction. For the synthesis of dicarba-β-d-isomaltose derivatives, the carbaglucosyl triflate locked in
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3997bf49e13840bd4225ba1f1bfdbdb1 https://pubmed.ncbi.nlm.nih.gov/30606671 Zobrazit plný text záznamu Full Text from ScienceDirect