| Autor: |
Hiroshi, Iijima, Katsuki, Takebe, Mamoru, Suzuki, Hiroko, Kobayashi, Tomoko, Takamiya, Hiroaki, Saito, Norio, Niwa, Takao, Kuwada-Kusunose |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Chemicalpharmaceutical bulletin. 68(5) |
| ISSN: |
1347-5223 |
| Popis: |
Catechol O-methyltransferase (COMT) is known as an important drug-target protein in the field of Parkinson's disease. All clinically approved COMT inhibitors bring a 5-substituted-3-nitrocatechol ring as a pharmacophore, and they bind to COMT with S-adenosylmethionine (SAM) and an Mg |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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