GABAergic deficits in absence of LPA

Autor: Cristina, Rosell-Valle, Magdalena, Martínez-Losa, Elisa, Matas-Rico, Estela, Castilla-Ortega, Emma, Zambrana-Infantes, Ana Isabel, Gómez-Conde, Lourdes, Sánchez-Salido, David, Ladrón de Guevara-Miranda, Carmen, Pedraza, Pedro Jesús, Serrano-Castro, Jerold, Chun, Fernando, Rodríguez de Fonseca, Manuel, Álvarez-Dolado, Luis Javier, Santín, Guillermo, Estivill-Torrús
Rok vydání: 2020
Předmět:
Zdroj: Brain structurefunction. 226(5)
ISSN: 1863-2661
Popis: Defects in GABAergic function can cause anxiety- and depression-like behaviors among other neuropsychiatric disorders. Therapeutic strategies using the transplantation of GABAergic interneuron progenitors derived from the medial ganglionic eminence (MGE) into the adult hippocampus reversed the symptomatology in multiple rodent models of interneuron-related pathologies. In turn, the lysophosphatidic acid receptor LPA
Databáze: OpenAIRE