| Autor: |
L, Dieminger, W, Vogt, R, Lynen |
| Rok vydání: |
1976 |
| Předmět: |
|
| Zdroj: |
Zeitschrift fur Immunitatsforschung. Immunobiology. 152(3) |
| ISSN: |
0340-904X |
| Popis: |
Factor D has been purified by gel and ion exchange chromatographies, and by ultrafiltration through different membranes. The final preparation appeared pure in various analytical tests. The molecular weight of human D is 21,500 according to gel chromatography, the isoelectric point was found at pH 7.8. Factor D is an active esterolytic enzyme, it cleaves N-alpha-acetyl-L-lysine methyl ester and N-alpha-acetyl-L-glycyl-L-lysine methyl ester. Both peptide esters inhibit the hydrolytic activation of factor B by D in the presence of cobra venom factor. D is also inhibited by diisopropyl-fluorophosphate and by penylmethyl-sulfonyl-flouride. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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