| Autor: |
Hajime, Sawada, Michiyo, Esaki, Hong-Ming, Sheng, Asami, Kita, Toyokazu, Yoshida |
| Rok vydání: |
2004 |
| Předmět: |
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| Zdroj: |
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 12(1) |
| ISSN: |
1067-1927 |
| Popis: |
Certain hollow organs are known to form cysts when heterologously transplanted. In order to examine the usefulness of the phenomenon for regenerative medicine, rat urinary bladders and other organs were allo-transplanted under the subcutaneous tissue of the back. These transplanted tissues very often formed cysts covered with epithelia. The epithelia covered an area about twice the original size. In the case of the urinary bladder, the epithelium started moving from the edge of the transplants around day 3 after the operation, and as time proceeded, the tela submucosa and tunica muscularis also moved to encircle the epithelium, and formed the wall of the cyst. The basal laminae were formed under the newly expanded epithelium slightly behind the leading tip. All of the organs tested had the capability of cyst formation and epithelialization, although their rate differed between organs. The results are discussed with reference to the potential use of cyst formation for regenerating damaged organs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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