Demonstration of fibronectin in soft tissue tumours using the immunoperoxidase technique
Autor: | C E, Du Boulay |
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Rok vydání: | 1982 |
Předmět: | |
Zdroj: | Diagnostic histopathology. 5(4) |
ISSN: | 0272-7749 |
Popis: | A variety of reactive, benign and malignant soft tissue lesions have been stained for fibronectin using the immunoperoxidase technique. Two patterns of mesenchymal staining have emerged. The first has a diffuse stromal collagen and basement membrane distribution within normal and neoplastic mesenchyme and the second a more specific intracytoplasmic granular staining pattern. The latter is seen only in lesions derived from fibrous-histiocytic and synovial cells, a finding which may be of diagnostic use. The possible significance of intracellular fibronectin in neoplastic mesenchyme is discussed. |
Databáze: | OpenAIRE |
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