Gender impact on first trimester markers in Down syndrome screening

Autor:	Severin Olesen, Larsen, Karen R, Wøjdemann, Anne-Cathrine, Shalmi, Karin, Sundberg, Michael, Christiansen, Ann, Tabor
Rok vydání:	2002
Předmět:	Adult Male Sex Characteristics Denmark Pregnancy Trimester First Pregnancy Prenatal Diagnosis Humans Mass Screening Pregnancy-Associated Plasma Protein-A Chorionic Gonadotropin beta Subunit Human Female alpha-Fetoproteins Down Syndrome Biomarkers Neck Ultrasonography
Zdroj:	Prenatal diagnosis. 22(13)
ISSN:	0197-3851
Popis:	The influence of fetal gender on the level in the first trimester of the serological markers alpha-fetoprotein (AFP), pregnancy-associated plasma protein-A (PAPP-A) and free beta human chorionic gonadotropin (betahCG) and on nuchal translucency is described for 2637 singleton pregnancies with normal outcome. Mean log MoM values for pregnancies with female and male fetuses were calculated using regression of log marker values on gestational age expressed as crown rump length and on maternal weight. A pronounced gender impact was found for free betahCG, being 16% higher for female than for male fetuses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::384e0533d26c6b915b3ff16afb13c4a7 https://pubmed.ncbi.nlm.nih.gov/12478634 Zobrazit plný text záznamu Plný text