Hypertrophic and keloid scars fail to progress from the CD34

Autor:	G C, Limandjaja, J M, Belien, R J, Scheper, F B, Niessen, S, Gibbs
Rok vydání:	2019
Předmět:	Phenotype Cicatrix Hypertrophic Keloid Humans Muscle Smooth Actins
Zdroj:	The British journal of dermatologyReferences. 182(4)
ISSN:	1365-2133
Popis:	Our understanding of the pathogenesis underlying keloid scar formation is still very limited, and the morphological distinction between hypertrophic and keloid scars remains difficult.To test whether hypertrophic and keloid scars may reflect an inability to progress from immaturity to the desired mature normotrophic scar phenotype.Using whole-biopsy imaging and an objectively quantifiable way to analyse immunoreactivity, we have compared the immunohistopathological profiles of young immature scars with mature normotrophic scars, hypertrophic scars, and keloids with their surrounding-normal-skin.Abnormal scars (hypertrophic scars and keloids) maintain the immature scar phenotype, characterized by a CD34Both abnormal scar types showed a unique CD34
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::383ab82e5d18766224630c65cedaf0c8 https://pubmed.ncbi.nlm.nih.gov/31494925 Zobrazit plný text záznamu Plný text