| Autor: |
Lingfang, Wang, Guankai, Zhan, Yasen, Maimaitiyiming, Yingfeng, Su, Shitong, Lin, Jinfeng, Liu, Kunhui, Su, Jiebo, Lin, Shizhen, Shen, Wentao, He, Fenfen, Wang, Jiafeng, Chen, Siqi, Sun, Yite, Xue, Jiaxin, Gu, Xiaojing, Chen, Jian, Zhang, Lu, Zhang, Qianqian, Wang, Kao-Jung, Chang, Shih-Hwa, Chiou, Mikael, Björklund, Hua, Naranmandura, Xiaodong, Cheng, Chih-Hung, Hsu |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Cell reports. 41(4) |
| ISSN: |
2211-1247 |
| Popis: |
Human papillomavirus (HPV)-induced carcinogenesis critically depends on the viral early protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 messenger RNA (mRNA)-containing oncotranscript complex can be selectively targeted by heat treatment. In HPV-infected cells, viral E7 mRNA is modified by N |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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