Neurite Orientation Dispersion and Density Imaging of Rat Brain Microstructural Changes due to Middle Cerebral Artery Occlusion at a 3T MRI

Autor:	Zhen-Xiong, Wang, Wen-Zhen, Zhu, Shun, Zhang, Mehran, Shaghaghi, Ke-Jia, Cai
Rok vydání:	2020
Předmět:	Male Neurites Animals Brain Infarction Middle Cerebral Artery Rats Wistar Magnetic Resonance Imaging Sensitivity and Specificity Rats
Zdroj:	Current medical science. 41(1)
ISSN:	2523-899X
Popis:	The purpose of this work was to demonstrate the feasibility of neurite orientation dispersion and density imaging (NODDI) in characterizing the brain tissue microstructural changes of middle cerebral artery occlusion (MCAO) in rats at 3T MRI, and to validate NODDI metrics with histology. A multi-shell diffusion MRI protocol was performed on 11 MCAO rats and 10 control rats at different post-operation time points of 0.5, 2, 6, 12, 24 and 72 h. NODDI orientation dispersion index (ODI) and intracellular volume fraction (V
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3731680c0c95a26651fcc7fe9f1e8605 https://pubmed.ncbi.nlm.nih.gov/33582922 Zobrazit plný text záznamu Full text from SpringerLink