| Autor: |
Silvia, Ghimpu, Laura, Bozomitu, E, Cîrdei, Doina, Mihlăilă, D, Boldureanu, D, Moraru |
| Jazyk: |
Romanian; Moldavian; Moldovan |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 114(1) |
| ISSN: |
0048-7848 |
| Popis: |
The purpose of of this study is to identify IELs through immunocytochemistry stains for counting infiltration duodenal mucosa with T lymphocytes in children with celiac disease.It was selected up simptomatology (abdominal pain, anorexia, failure thrive, chronic diarheea), features immunology(positifs tissue transglutaminase antibodies) and considering the histopathologic results (IELs30/100 enterocytes, crypt hyperplasia and villous atrophy) we made two groups: first group (13 children with celiac disease of 53 children with celiac disease) and second group (13 children with chronic duodenitis nonspecific). For evidence of intraepithelial lymphocytes T using immunocytochemistry tehnicque (immunohistochemical staining) Envision with antibody anti CD 3 from Dako firme. Corresponding Marsh clasification considering patological IELs30/100 enterocytes. Statitics method was used The Student' t test.Analyse IELs in two groups our show difference statistics to demonstrate with the Student' t test (t = -12.237; p = 0.003).An increase IELs is helpful in recognising early and bordeline, but the finding is not specific. The histopathologic exam remains the gold standard for celiac disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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