Response to thalidomide in chemotherapy-resistant mantle cell lymphoma: a case report

Autor:	Edward A, Wilson, Shialesh, Jobanputra, Robert, Jackson, Anne N, Parker, I Grant, McQuaker
Rok vydání:	2002
Předmět:	Male Fatal Outcome Drug Resistance Neoplasm Recurrence Humans Angiogenesis Inhibitors Antineoplastic Agents Lymphoma Mantle-Cell Aged Thalidomide
Zdroj:	British journal of haematology. 119(1)
ISSN:	0007-1048
Popis:	Mantle cell lymphoma is an aggressive B-cell lymphoma with a poor median survival despite conventional therapy. Here, we present the case of a patient with multiply relapsed mantle cell lymphoma, having failed treatment with chemotherapy, steroids and rituximab. He was treated with single-agent thalidomide at a dose of 800 mg daily and entered a good partial remission which was maintained for the next 6 months. There is clearly a need for further studies of thalidomide in mantle cell lymphoma to confirm this promising initial result.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::36f6a94dbb547f99ae26222101d42f59 https://pubmed.ncbi.nlm.nih.gov/12358916 Zobrazit plný text záznamu Plný text