Association of

Autor:	Nannan, Wang, Xinyu, Chen, Zhuolu, Hao, Honggang, Yi, Shaowen, Tang
Rok vydání:	2022
Předmět:	Male China Genotype Haplotypes Case-Control Studies Antitubercular Agents ATP Binding Cassette Transporter Subfamily G Member 2 Humans Genetic Predisposition to Disease Prospective Studies Chemical and Drug Induced Liver Injury Polymorphism Single Nucleotide Neoplasm Proteins
Zdroj:	Xenobiotica; the fate of foreign compounds in biological systems. 52(5)
ISSN:	1366-5928
Popis:	The accumulation of endogenous hepatotoxin protoporphyrin IX (PPIX) in the liver was proposed to be a novel mechanism of anti-tuberculosis drug-induced hepatotoxicity (ATDH). ATP-binding cassette transporter G2 (ABCG2) plays an important role in modulating PPIX concentrations. This study aimed to explore the role of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::364f13c10e3767896b4c3c55b0c07c67 https://pubmed.ncbi.nlm.nih.gov/35735268 Zobrazit plný text záznamu