| Autor: |
P, Blanc, J P, Daurès, J, Liautard, R, Buttigieg, D, Desprez, G, Pageaux, J L, Allaz, G, Parelon, D, Larrey, H, Michel |
| Jazyk: |
francouzština |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Gastroenterologie clinique et biologique. 18(12) |
| ISSN: |
0399-8320 |
| Popis: |
The effectiveness of the association of lactulose with neomycin in the treatment of acute hepatic encephalopathy has never been assessed. The aim of this study was to compare the effects of lactulose-neomycin combination versus placebo in acute hepatic encephalopathy.Eighty patients with cirrhosis were randomly treated for 5 days with placebo (n = 40) or with lactulose-neomycin (n = 40). Both groups were similar for all variables.The course of encephalopathy was similar in both groups. In the lactulose-neomycin group: 26 PATIENTS recovered, 3 remained unchanged, 3 worsened, 6 died, 2 were lost to follow-up. In the placebo group: 28 recovered, 2 remained unchanged, 2 worsened, 6 died, one was lost the follow-up, one dropped out of the study. Lactulose-neomycin treatment was not well tolerated in a significant number of patients.Lactulose-neomycin combination should not be used in the treatment of acute hepatic encephalopathy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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