The value of 18F-FDG PET/CT in patient with neurofibromatosis type 1
| Autor: | Ren, Jiazhong, Yang, Guoren, Zhou, Jing, Fu, Zheng |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Rationale: Neurofibromatosis type one (NF1) is characterized by cutaneous and nervous lesions, and the tendency to form plexiform neurofibromas (PNFs). PNFs may undergo malignant transformation into a malignant peripheral nerve sheath tumors (MPNSTs). MPNSTs often carry an significant morbidity and mortality. Patient concerns: A 17-year-old man with gradually increased multiple subcutaneous soft lesions. He also presented with numerous lentigines and multiple café-au-lait macules on his body. Diagnoses: These were collagen neurofibroma, which were definitively diagnosed by pathology. NF1 was eventually diagnosed. Interventions: These lesions were abnormal uptake of radiotracer, when he underwent positron emission tomography (PET) with fluorine-18-fluorodeoxyglucose (FDG) scanning. Standard uptake value (SUV) and other parameters can help to distinguish benign and malignant lesions in patient with NF1. He was underwent serials 18F-FDG PET/CT examinations to followed up, in order to monitor these lesions malignant transformation. Outcomes: So far, these subcutaneous soft lesions were not malignant transformation. Lessons: 18F-FDG PET/CT is being increasingly used as an imaging modality to discover the systemic lesions and to discriminate between benign and malignant plexiform neurofibromas. |
| Databáze: | OpenAIRE |
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