Autor: |
N, Parry-Jones, M E, Gore, J, Taylor, J G, Treleaven |
Rok vydání: |
2000 |
Předmět: |
|
Zdroj: |
Clinical and laboratory haematology. 21(6) |
ISSN: |
0141-9854 |
Popis: |
Anti-M is usually a naturally occurring cold-reactive immunoglobulin M (IgM) antibody, often with an immunoglobulin G (IgG) component, and is seldom implicated in delayed haemolytic transfusion reactions (DHTR). However, cases have been reported. In the majority, a DHTR is not suspected until further blood is requested and a new antibody is detected on pretransfusion testing. We describe the case of a young man receiving therapy with interleukin-2 (IL-2) and interferon-alpha (IFN-alpha) for metastatic renal cell cancer who developed a clinically suspected DHTR that was confirmed serologically to be caused by anti-M, reactive at 37 degrees C. We discuss the possible role of his biochemotherapy in the development of the DHTR. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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