Autor: |
Hongwei, Wang, Jie, Li, Liang, Tao, Luting, Lv, Jinghui, Sun, Tengteng, Zhang, Huimin, Wang, Jiandong, Wang |
Rok vydání: |
2021 |
Zdroj: |
Iranian journal of public health. 51(7) |
ISSN: |
2251-6093 |
Popis: |
We explored the methylation modification in miR-205 promoter during the pathological changes of Parkinson's disease (PD) and its regulation onMethylation of miR-205 promoter regions was determined by cell genomic DNA, with model bisulfite treatment, and the transcription of miR-205 andThe level of miR-205 were reduced in the SH-SY5Y Parkinson model cells, and its promoter region was highly methylated, whileThe methylation modification of miR-205 promoter region could regulate the transcription and translation of |
Databáze: |
OpenAIRE |
Externí odkaz: |
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