| Autor: |
O V, Bagryantseva, I V, Gmoshinski, V A, Shipelin, S A, Sheveleva, N A, Riger, A A, Shumakova, N R, Efimochkina, Yu M, Markova, N V, Tsurikova, Yu V, Smotrina, I E, Sokolov, A I, Kolobanov, S A, Khotimchenko |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Voprosy pitaniia. 91(3) |
| ISSN: |
0042-8833 |
| Popis: |
The requirements for the safety of food products obtained by microbial synthesis are including as obligation for to conduct toxicological studies - the study of various biochemical and immunological markers of toxic effects. The necessity of these studies is explained by a possible change in the structure of food ingredients produced by a microbial cell and, consequently, a change in their biological properties, as well as the possible presence of living forms and/or DNA of producer strains or of their toxic metabolites in these ingredients. At the same time, it is well known that the nutrient composition of foods has a significant impact on the composition and properties of microorganisms that make up the gut microbiome, which, in turn, determines the immune status. The purpose of the research was to justify the analyses of gut microbiocenosis composition for inclusion in the protocol of safety investigation of foods obtained by microbial synthesis [on the example of an enzyme preparation (EP) - a complex of glucoamylase and xylanase from a genetically modified strain of Aspergillus awamori Xyl T-15]. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
