[Preparation of a dry red blood cell Trichinella antigenic diagnosticum for indirect hemagglutination test and evaluation of its efficiency]

Autor:	T I, Tverdokhlebova, Iu I, Vaserin
Rok vydání:	2005
Předmět:	Erythrocytes Sheep Evaluation Studies as Topic Antigens Helminth Animals Humans Trichinellosis Hemagglutination Tests Reagent Kits Diagnostic Sensitivity and Specificity Rats Trichinella spiralis
Zdroj:	Meditsinskaia parazitologiia i parazitarnye bolezni. (2)
ISSN:	0025-8326
Popis:	The present paper presents the stages of a process for manufacturing a dry red blood cell Trichinella antigenic diagnosticum for indirect hemagglutination test (IHAT) and the evaluation of its diagnostic efficiency. The diagnosticum is shown to be a 3% suspension lyophilized from formalinized and tanned sheep red blood cells on which an excretory-secretory antigen of invasion Trichinella larvae was absorbed in a dose of 100 mg/ml. The rather high sensitivity (98.7%) and specificity (97.3%) of IHAT using the Trichinella diagnosticum based on the excretory-secretory antigen allow it to be considered an effective method for diagnosis of human trichinosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::34a10c655498b4fade0630b0b900d367 https://pubmed.ncbi.nlm.nih.gov/15984615 Zobrazit plný text záznamu