[Carcinogenic activity of dioxidine]

Autor: L F, Shashkina, V M, Ivanova, O I, Lavrik, V A, Proĭnova, L V, Nechushkina
Rok vydání: 1985
Předmět:
Zdroj: Farmakologiia i toksikologiia. 48(1)
ISSN: 0014-8318
Popis: A study was made of the blastomogenic activity of dioxydin, a new antibacterial broad-action drug. Administration of dioxydin in doses of 20-100 mg/kg (exceeding 2-10-fold the therapeutic dose for humans) to mice and rats intragastrically for 18 months and intraperitoneally (2 years of observation) as well as combined administration of the drug to rats transplacentally and postnatally (1.5 years of observation) did not induce any neoplasms.
Databáze: OpenAIRE